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2-Fmoc-8-(tert-butoxycarbonyl)-2,8-diazaspiro[4.5]decane-3-carboxylic acid is a Amino Acid reagent (Subcategory: Unusual AA) sold by WuXi TIDES. Offered in 100 g. Store at 4 °C. SDS available for reference.
Specifications - CAS: 849928-23-0 - MDL: MFCD07779072 - InChIKey: URRGFGKYPWMHCY-UHFFFAOYSA-N - Molecular Weight: 506.599 - Molecular Formula: C29H34N2O6 - Purity: ≥95% - Container Type: 500 mL HDPE - Pack Size: 100 g - Net Weight: 100 g - Gross Weight: 160.5 g - Commodity Code: 29339980 - Country Of Origin: China - IUPAC: 2-(((9H-fluoren-9-yl)methoxy)carbonyl)-8-(tert-butoxycarbonyl)-2,8-diazaspiro[4.5]decane-3-carboxylic acid - SMILES: CC(C)(OC(N1CCC2(CC(N(C(OCC3C4=C(C5=C3C=CC=C5)C=CC=C4)=O)C2)C(O)=O)CC1)=O)C
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PEG-bis-amine (MW 20000) is a poly(ethylene glycol)-based PROTAC linker, primarily utilized in the synthesis of Proteolysis Targeting Chimeras (PROTACs). These PROTACs leverage the intracellular ubiquitin-proteasome system for the selective degradation of target proteins. The compound has an average molecular weight of 20000 and typically appears as a white to off-white solid, with a purity of 98.0%.
PEG-based linker for PROTAC synthesis
Enables targeted protein degradation via ubiquitin-proteasome system
White to off-white solid appearance
Average molecular weight of 20000
98.0% purity
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If you are unable to find the chemical you are looking for, make sure you are logged into your fishersci.com account and click on the following link: eMolecules Building Block Tool<|a>
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TQS is a selective positive allosteric modulator of the α7 nicotinic acetylcholine receptor (nAChR) used in preclinical research, including studies of neuroinflammatory pain. It is provided as a high-purity research chemical and is available as a powder or as a DMSO solution for experimental use.
Selective α7 positive allosteric modulator for receptor modulation studies.
Suitable for in vitro and in vivo neuroinflammatory pain research.
High purity (~99.8%).
Available as powder and as a 10 mM solution in DMSO.
Recommended storage: powder -20 °C long term or 4 °C short term; in solvent -80 °C.
Molecular formula C22H20N2O2S and molecular weight 376.47 g·mol-1.
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RP-1664 is a selective and orally active PLK4 inhibitor with an IC50 of 3 nM. It demonstrates selectivity over related kinases like AURKA/B and PLK1. This compound disrupts centriole biogenesis in cancer cells, leading to an accumulation of PLK4 and p21 protein. RP-1664 shows increased sensitivity in TRIM37-high-expressing cells or tumors and exhibits anti-tumor activity in breast cancer and neuroblastoma research.
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